pentobarbital will lessen the level or influence of pitolisant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Pitolisant exposure is lessened by 50% if coadministered with strong CYP3A4 inducers.

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pentobarbital decreases levels of amphotericin B deoxycholate by inhibition of GI absorption. Applies only to oral kind of both of those brokers. Small/Importance Unknown.

pentobarbital will reduce the level or influence of lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with strong CYP3A4 inducers may end up in diminished serum concentrations and lack of antimalarial efficacy

pentobarbital will lower the extent or outcome of tamoxifen by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

pentobarbital will lessen the extent or impact of estropipate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

Observe Carefully (two)pentobarbital will lessen the level or influence of suvorexant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Solid CYP3A4 inducers may possibly decrease suvorexant efficacy; if greater suvorexant dose necessary, do not exceed 20 mg/day

pentobarbital will lessen the extent or result of sulfamethoxazole by influencing hepatic enzyme CYP2C9/10 metabolism. Small/Significance Unidentified.

Contraindicated (one)pentobarbital will minimize the level or result of dienogest/estradiol valerate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Gals mustn't pick out estradiol valerate/dienogest as their contraceptive although employing solid CYP3A4 inducers as a consequence of potential minimize in contraceptive efficacy.

pentobarbital will decrease the level or result of isradipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unidentified.

pentobarbital will lessen the extent or outcome of diazepam intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Potent or moderate CYP3A4 inducers may enhance rate of diazepam elimination; thus, efficacy of diazepam website might be lowered.

pentobarbital will minimize the level or impact of fostemsavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.

pentobarbital decreases levels of elvitegravir/cobicistat/emtricitabine/tenofovir DF by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Might bring about loss of virologic response and possible resistance.

pentobarbital will minimize the level or impact of diltiazem by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.